Tutorial Videos

Basic Concepts and Systems

Basic Concepts

Free-Running Periods

This video was made by two trainees at UCSD's Center for Circadian Biology (Ben Sheredos and Liz Harrison) for use in the undergraduate class on circadian rhythms and biological clocks at UCSD.

Naming Conventions

This video was made by two trainees at UCSD's Center for Circadian Biology (Liz Harrison and Ben Sheredos) for use in the undergraduate class on circadian rhythms and biological clocks at UCSD.

Phase Response Curves

This video was made by two trainees at UCSD's Center for Circadian Biology (Liz Harrison and Ben Sheredos) for use in the undergraduate class on circadian rhythms and biological clocks at UCSD.

Understanding the Actogram

In this video Dr. Michael Gorman of UC San Diego breaks down how running-wheel data are plotted in an actogram and how to interpret this type of _gure.

Cyanobacterial Systems

Cyanobacterial Circadian Oscillator

This animation demonstrates the circadian oscillator mechanism in the cyanobacterium Synechococcus elongatus. It was produced and developed by members of the BioClock Studio Winter 2016 at UC San Diego.

Cyanobacterial Circadian Clock Output Mechanism

This animation shows how the core circadian oscillator in the cyanobacterium Synechococcus elongatus sends output to regulate the timing of other intracellular processes. It was produced and developed by members of the BioClock Studio Winter 2016 at UC San Diego.

Plant Systems

Photoperiodic Flowering - Part 1

This video tutorial was produced by members of the BioClock Studio Winter 2017 at UC San Diego. It describes how plants decide when it’s time to flower based on their ability to precisely measure day- and night-lengths, a phenomenon that is called “Photoperiodic Flowering."

Photoperiodic Flowering - Part 2

This video tutorial was produced by members of the BioClock Studio Winter 2017 at UC San Diego. It describes molecular mechanism of Photoperiodic Flowering, called the External Coincidence Model.

Insect Systems

Time-Memory in Bees: Demonstration That Organisms Tell 24-Hour Time

This video tutorial describes how the early circadian rhythm researchers demonstrated the organisms's behavior is governed by internal biological clocks as opposed to external time-cues. It was produced and developed by members of the BioClock Studio Winter 2017 at UC San Diego.

Mammalian Systems

Mammalian Retina and Photoreceptors

This tutorial video was produced by members of the BioClock Studio Winter 2016 at UC San Diego and clarifies the anatomy and function of neural circuits for image-forming and non-image-forming vision.

2-Process Model of Sleep

This tutorial was produced by members of the BioClock Studio Winter 2016 at UC San Diego, and clarifies how sleep homeostasis and the circadian clock are hypothesized to interact to determine the sleep-wake cycle.

Demystifying Circadian Lab Techniques

Methods

Neurobiology - The Neuron

This video was made by two trainees at UCSD's Center for Circadian Biology (Liz Harrison and Ben Sheredos) for use in the undergraduate class on circadian rhythms and biological clocks at UCSD.

Neurobiology Techniques

This video was made by two trainees at UCSD's Center for Circadian Biology (Liz Harrison and Ben Sheredos) for use in the undergraduate class on circadian rhythms and biological clocks at UCSD.

Luciferase Reporters in Circadian Research

This video was made by the BioClock Studio for use in an upper division undergraduate class on circadian rhythms and biological clocks at UC San Diego.

The Suprachiasmatic Nucleus: Lesion & Transplant Experiments Review

This video tutorial was produced by members of the BioClock Studio Winter 2017 at UC San Diego. It describes landmark experiments involving SCN lesions and SCN transplants with Tau mutant hamsters, which demonstrated the role of the SCN as the central mammalian pacemaker.

Fluence Response Curves and Action Spectra (Part 1 of 3)

This tutorial, produced and developed by members of the BioClock Studio Winter 2017 at UC San Diego, explains how we can study the effects of light beyon eing, specifically, non-image forming vision.

Fluence Response Curves and Action Spectra (Part 2 of 3)

This video tutorial, produced by members of the BioClock Studio Winter 2017 at UC San Diego, explains how fluence response curves are built from experimental data.

Fluence Response Curves and Action Spectra (Part 3 of 3)

This video tutorial, produced and developed by members of the BioClock Studio Winter 2017 at UC San Diego, explains how action spectra is made from fluence response curves.

In Lab Videos

Setting Up a Wheel-Running Experiment

This video presents the practical considerations for setting up a rodent wheel-running experiment and explains how the instrumentation works.

Performing a Wheel-Running Experiment

This video shows how data are collected and the environmental conditions are controlled during a wheel-running experiment.

Analyzing Data from a Wheel-Running Experiment

This video demonstrates the computer programs that are used to extract and transform the raw data for analysis by researchers.

Luciferase Reporters for Mammals in Circadian Research

This in-lab video was produced by members of the BioClock Studio Winter 2016 at UC San Diego and shows the use of luciferase reporters in mice for circadian research.

Luciferase Reporters for Cyanobacteria in Circadian Research

This in-lab video was produced by members of the BioClock Studio Winter 2016 at UC San Diego and shows the use of luciferase reporters in cyanobacteria for circadian research.